Ranomics' promoter activity analysis platform is well-suited for the characterization of promoter activity in a high-throughput and quantitative manner. This platform is ideal for optimizing the expression of specific genes and proteins in a synthetic cell. 

 

Highly diverse promoter libraries are synthesized using VariantFind technology, followed by precise integration of promoter variants into mammalian cells or transformation into yeast or bacteria cells.

 

By combining promoter variants with a barcoded gene of interest or flourescent protein reporters, Ranomics can measure mRNA transcript levels or protein expression levels using next generation sequencing or flow cytometry, respectively. 

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Using this approach, our partners can find the optimal promoter sequences for any gene or protein of choice.