Engineer better biologics, faster
AI-driven protein binder design and protein engineering for biotech and biopharma — combining computational design with high-throughput display screening, deep mutational scanning, and directed evolution
Full-stack protein and cell engineering
Computational design, experimental screening, and variant characterization — all under one roof.
Protein engineering
Optimize function, stability, and expression through deep mutational scanning, affinity maturation, and rational design.
Cell engineering
CRISPR gene editing, stable and reporter cell line development with landing pad technology, large-scale vector construction, and lentiviral vector production.
Directed evolution
Random and focused mutagenesis libraries screened by display or functional assay. Iterative rounds of selection to evolve proteins.
AI protein binder design
De novo binders designed computationally with RFdiffusion, BindCraft, and Boltzgen, then validated experimentally through display.
Deep mutational scanning
Comprehensive fitness landscapes mapping binding, expression, stability, and function across thousands of variants in one experiment.
AI enzyme engineering
Computationally guided enzyme optimization for activity, thermostability, and substrate specificity using structure-based design and directed evolution.
AI Binder Sprint
A fixed-scope program combining computational design with experimental validation. You provide a target structure — we guarantee binder identification using RFdiffusion, BindCraft, Boltzgen, and yeast display screening.
Guaranteed binder identification or your money back.
Epitope Scout
Identify and rank candidate surface epitopes on your target protein for de novo binder design. Upload a PDB structure, get scored epitope patches ready for RFdiffusion and BindCraft.
Sign up for free to access the tool. No credit card required.
Your strategic partner in biologic development
For nearly a decade, we have operated as a seamless extension of our clients' teams. From custom DNA variant libraries to high-throughput screening, our services have powered over 100 successful projects across pharma, biotech, and academic research.
Whether your goal is a breakthrough publication, validating a pre-clinical asset, or discovering novel binders from scratch — our team is your dedicated resource for achieving it.
Talk to our team →
Computational and experimental platforms, integrated
See all platforms →High-throughput protein variant screening on yeast cell surfaces. FACS and MACS selection.
Display on mammalian cells for targets requiring native post-translational modifications.
Comprehensive fitness landscapes across thousands of single and combinatorial mutations.
Iterative mutagenesis and selection to optimize protein function, stability, and expression.
Structure-guided diffusion model generating de novo protein backbones from target hotspots.
Iterative binder design with integrated scaffold generation and sequence scoring.
Boltzmann-weighted conformational sampling for protein structure ensembles and stability prediction.
Next-gen sequencing pipeline for quantitative, reproducible hit calling and ranking.
Trusted by 100+ biotechnology companies
From seed-stage biotech to Fortune 500 pharma and leading research institutions
Working with Ranomics was a positive experience. They consulted with me extensively to ensure I was getting exactly the product I needed.
University of Waterloo
We recently performed specific mutagenesis of all six CDRs in a single scFv antibody sequence with Ranomics. We were very pleased with the mutation diversity that was obtained and were impressed with how specific (and fast) the mutations could be introduced to make a new library.
Grifols
We are very pleased with the diversity and specific composition of the synthetic variant libraries produced by Ranomics. Our projects were executed on time or ahead of schedule and throughout the process Leo and Jonathan were always available to answer any questions we had.
Obsidian Therapeutics
The Biologics Playbook
A practical guide to cell display technologies for protein engineering teams. Covers yeast display, mammalian display, and selection strategies.
Ready to start a project?
Tell us about your protein or cell engineering challenge. We'll scope a program and get back to you within 24 hours.
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