What are you trying to achieve?
Protein engineering applications from de novo binder discovery and affinity maturation to enzyme engineering and antibody design
De novo binder discovery
Design novel protein binders for targets with no existing leads. Computational design generates candidates; display screening validates them. For novel targets, challenging epitopes, and programs where library approaches have failed.
Affinity maturation
Improve the binding affinity of existing protein leads through targeted mutagenesis and iterative display selection. Map the full fitness landscape, identify beneficial mutations, and combine them for optimized variants.
Enzyme engineering
Engineer enzyme activity, thermostability, substrate specificity, and expression yield. Computational assessment, directed evolution, and high-throughput screening for industrial, therapeutic, and diagnostic enzymes.
Antibody & nanobody engineering
VHH nanobody design and optimization, scFv and Fab engineering, humanization, and developability screening. Display-based selection coupled to NGS characterization for full candidate profiles.
Receptor targeting
Designing protein binders for GPCRs, ion channels, and receptor tyrosine kinases — targets where conventional library approaches struggle. De novo computational design excels for complex membrane targets.
Don't see your application?
We work across a wide range of protein and cell engineering applications. Tell us about your target and goals — we'll scope a program.
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